Abstract Library

#2882 Impact of Ga68-DOTATOC PET/MRI on Therapy Management in Patients with Neuroendocrine Neoplasia (NEN) - Preliminary Results

Introduction: Integrated PET/MRI combines the sensitivity and functional relevance of PET imaging and the spatial resolution and soft tissue contrast of MRI.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Amthauer H

Authors: Radojewski P, Nagel S, Fehrenbach U, Jann H, Rogasch J,

Keywords: PET/MRI, 68Ga-DOTATOC, neuroendocrine neoplasm, therapeutic strategy,

#2682 PAK4-NAMPT Dual Inhibition as a Novel Strategy for Therapy Resistant Pancreatic Neuroendocrine Tumors

Introduction: Pancreatic neuroendocrine tumors (PNET) remain an unmet clinical need. In this study, we show that targeting both nicotinamide phosphoribosyltransferase (NAMPT) and p21-activated kinase 4 (PAK4) could become a synthetic lethal strategy for PNET.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Mpilla G

Authors: Mpilla G, Aboukameel A, Muqbil I, Kim S, Philip P,

Keywords: pak4, nampt, mtor, pancreatic neuroendocrine tumors, kpt-9274,

#2250 Treatment Outcomes of Patients with Mixed Neuroendocrine Non-Neuroendocrine Neoplasms (MiNEN)

Introduction: Mixed neuroendocrine non-neuroendocrine neoplasms (MiNEN) have been newly defined in the WHO 2017 classification. They are rare tumors, commonly treated in analogy to their non-neuroendocrine (nNE) or neuroendocrine (NE) component without systematic data regarding the optimal therapeutic strategy.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Apostolidis L, Bergmann F, Haag G, Jäger D, Winkler E,

Keywords: MiNEN, mixed neuroendocrine non-neuroendocrine neoplasm, MANEC, mixed adenoneuroendocrine carcinoma,

#896 Grading of Metastases in Digestive Neuroendocrine Tumors (NET): Interest for Clinical Management?

Introduction: Therapeutic strategy of NETs is highly dependent on tumor classification according to the WHO system. NETs are frequently classified based on the histological characteristics of the primary tumor associated with the ENETS grading, even for patients with metastases.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Dumars C

Authors: Dumars C, Foubert F, Touchefeu Y, Regenet N, Senellart H,

Keywords: NET, grading,

#343 PCR Assessment of Carcinoid Lymph Node Metastasis CgA Transcript Outperforms Immunostaining, Tyramide Signal Amplification and H&E and Significantly Upstages Disease

Introduction: Accurate neuroendocrine tumor (NETs) staging is vital for determining therapeutic strategy. Sensitive techniques to facilitate identification of metastases (mets) are of critical clinical relevance.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Lawrence B, Kenney B, Kidd M, Modlin I,

Keywords: CgA, immunofluorescence, histopathology, lymph node, neuroendocrine tumor, PCR, tyramide, up-staging,